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Systolic Anterior Motion After Mitral Valve Repair: Is Surgical Intervention Necessary?

M. L. Brown, M. D. Abel, R. L. Click, H. V. Schaff. Mayo Clinic, Rochester, MN,


BACKGROUND: The natural history and management of patients with systolic anterior motion (SAM) after mitral valve (MV) repair is uncertain.
METHODS: Retrospective chart review and survey follow-up of all patients who developed SAM intraoperatively after MV repair.
RESULTS: From January 1993 to December 2002, MV repair was performed in 2,076 patients and in 168 cases (8.1%) SAM was identified on intraoperative echocardiography. These patients form the study group. Initially, patients were managed with a combination of β-blockade, vasoconstriction with phenylephrine, and/or intravascular volume expansion. Two patients had revision of repair due to persistent SAM and 3 additional patients due to mitral regurgitation from other causes. Median follow-up of the remaining 163 patients was 4.7 years (range: 0-12.3 years). There were 3 late re-operations, but none was caused by SAM or left ventricular outflow tract obstruction (LVOTO). Ninety percent of patients were in NYHA class I, 6% in class II, and 4% in class III or IV. Echocardiograms were available for review in 88 patients at a median interval of 4.7 years (range: 0.5-12.2 years); 12 patients had SAM and 4 had SAM with LVOTO.
CONCLUSIONS: In this experience, most cases of SAM resolved with conservative measures including β-blockade, vasoconstriction, and fluid administration. Persistent SAM with LVOTO was documented in 4.5% of patients who had early SAM, but did not lead to reoperation. Furthermore, the clinical outcomes of patients with SAM are comparable to current norms for MV repair.
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